AB0282 NEW INFLAMMATORY MARKER IN RHEUMATOID ARTHRITIS: NEUTROPHIL/LYMPHOCYTE RATIO (NLR)

Background Although neutrophils and lymphocytes play well-established roles in the pathogenesis of Rheumatoid arthritis (RA), their count is most often ignored by clinicians. However, neutrophil/lymphocyte ratio (NLR) seems to be great value evaluation disease activity. Objectives Our objective determine interest this study its relationship with other parameters RA Methods Cross-sectional 70 patients followed for RA. We performed a biological check-up including complete blood (CBC), an ESR CRP level. A NLR was calculated each patient. Results There were 58 women (82.9%) 12 men (17.1%) mean age 54.7 ± 13.6 years [19-82]. The duration 10.1± 9.9 years. Sixteen (22.8%) had recent (<2 years). DAS 28 5.38± 1.48. Thirty-nine (55.7%) high average 59 mmH1± 35 [12-150] 30.3 mg/l 28.6 [0-159], respectively. Anemia inflammation observed 43.3% cases. Lymphopenia found 28.6% cases, neutropenia 1.4% neutrophilic polynucleosis 17% 3.62±2.68 [0.48-13.26]. It 3.7 severe activity 3.5 those low moderate Statistical analysis significant association between anemia (p=0.003), (p=0.005), (p=0.038) assessed (p=0.04). Conclusion Despite fact that there are few studies evaluating NLR, our concludes considered as alternative inflammatory biomarker could used assess References [1] Lijuan W et al. Neutrophil-lymphocyte, platelet-lymphocyte lymphocyte-monocyte ratios may not useful markers rheumatoid arthritis: STROBE-compliant article. Medicine (Baltimore). 2021 Nov;100(45):e27631. [2] Uslu AU Two new associated Disease Activity Score-28 neutrophil-lymphocyte ratio. Int J Rheum Dis. 2015 Sep;18(7):731–5. Acknowledgements: NIL. Disclosure Interests None Declared.